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Sunday, August 25, 2013

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Molecular Biology of the Gene ,Watson

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Though completely up-to-date with the latest research advances, the Sixth Edition of James D. Watson’s classic book, Molecular Biology of the Gene retains the distinctive character of earlier editions that has made it the most widely used book in molecular biology. Twenty-two concise chapters, co-authored by six highly respected biologists, provide current, authoritative coverage of an exciting, fast-changing discipline. Mendelian View of the World, Nucleic Acids Convey Genetic Information,The Importance of Weak Chemical Interactions, The Importance of High Energy Bonds, Weak and Strong Bonds Determine Macromolecular Interactions, The Structures of DNA and RNA, Genome Structure, Chromatin and the Nucleosome, The Replication of DNA, The Mutability and Repair of DNA, Homologous Recombination at the Molecular Level, Site-Specific Recombination and Transposition of DNA, Mechanisms of Transcription 13 RNA Splicing, Translation, The Genetic Code, Transcriptional Regulation in Prokaryotes, Transcriptional Regulation in Eukaryotes, Regulatory RNAs, Gene Regulation in Development and Evolution, Genomics and Systems Biology, Techniques of Molecular Biology, Model Organisms. Intended for those interested in learning more about the basics of Molecular Biology.
PART 1: CHEMISTRY AND GENETICS
1. The Mendelian View of the World
2. Nucleic Acids Convey Genetic Information
3. The Importance of Weak Chemical Interactions
4. The Importance of High-Energy Bonds
5. Weak and Strong Bonds Determine Macromolecular Structure
PART 2: MAINTENANCE OF THE GENOME
6. The Structures of DNA and RNA
7. Genome Structure, Chromatin, and the Nucleosome
8. The Replication of DNA
9. The Mutability and Repair of DNA
10. Homologous Recombination at the Molecular Level
11. Site-specific Recombination and Transposition of DNA
PART 3: EXPRESSION OF THE GENOME
12. Mechanisms of Transcription
13. RNA Splicing
14. Translation
15. The Genetic Code
PART 4: REGULATION
16. Transcriptional Regulation in Prokaryotes
17. Transcriptional Regulation in Eukaryotes
18. Regulatory RNAs
19. Gene Regulation in Development and Evolution
20. Genome Analysis and Systems Biology
PART 5: METHODS
21. Techniques of Molecular Biology
22. Model Organisms

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