This book covers much of the same material as Stryer with about twice the detail and vastly better illustrations. V&V's massive advantage is a detailed methods chapter that lets you understand how the advances in biology have been made, and why science is so slow and frustrating. If you're serious about understanding biological chemistry (as distinct from understanding how the cell works, in which case you'll want a book on molecular cell biology), look no further than this. The third edition will becoming out in 2002, at about the same time as the sixth edition of Stryer. Expect V&V to be more up-to-date, better illustrated and less verbose than its competition (although obviously I haven't seen either yet). If you're a medical student, try Devlin's Biochemistry with clinical correlations. If you want an integrated cell biology/biochemistry text, try Garrett and Grisham, including part 5.
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